• Inner pillar cells express Fgfr which

  2018-11-06

  

  Inner pillar cells express Fgfr3, which may contribute to their capacity for regeneration (Jacques et al., 2007). Supporting cells in the chicken basilar papilla express Fgfr3, which is transiently downregulated during hair cell regeneration (Bermingham-McDonogh et al., 2001). Fgfr3−/− mice lack inn

• To stage rhesus and human PGCs

  2018-11-06

  

  To stage rhesus and human PGCs, we created a heatmap of diagnostic genes that represent early PGCs (prior to DAZL and VASA expression), late PGCs (DAZL and VASA positive but prior to the emergence of major sex-specific transcriptional differences), advanced PGCs (enrichment of the male-specific gene

• Direct genetic reprogramming of postnatal

  2018-11-06

  

  Direct genetic reprogramming of postnatal primary cells by forced expression of key developmental transcription factors has emerged as an alternative to in vitro differentiation of PSCs. This strategy has been used successfully to produce functional cells, including neurons, hepatocyte-like cells an

• Compared to the adherent monolayer culture

  2018-11-06

  

  Compared to the adherent monolayer culture, an alternative method using suspension culture has been shown to be more effective in obtaining and maintaining the early neural histone demethylase inhibitor emerged during multi-staged differentiation process. Using serum-free medium supplemented with e

• With regard to the functional analysis

  2018-11-06

  

  With regard to the functional analysis of DSCs and HGF-1, several in vitro tests were performed with endothelial glucose assay (HMEC-1) to assess their influence on the different steps of the angiogenic process. Despite the expression of multiple mitogens such as VEGF, EDN1, DPPIV and ANG, DSCs were

• br Materials and methods br Results br Discussion Obesity re

  2018-11-06

  

  Materials and methods Results Discussion Obesity results when caloric intake exceeds energy expenditure, with an increase in adipocyte size or adipocyte number (Bjorntorp, 1974; Faust et al., 1978; Johnson et al., 1971, 1978; Yu et al., 1997). In the context of adipogenesis, development app

• Studies in developmental biology have identified

  2018-11-06

  

  Studies in developmental biology have identified key regulators of morphogenetic properties, and have indicated where endogenous EMF is located in the action potentials of nerves and heart tissue, and in skeletal muscle vibrations, with frequencies elicited by rhythmic activities throughout the huma

• SAMHD emerges as a ubiquitous and potent barrier to producti

  2018-11-06

  

  SAMHD1 emerges as a ubiquitous and potent barrier to productive HIV-1 infection in DCs, myeloid cells, and resting CD4+ T cells. Thus, it appeared likely that SAMHD1 might also be effective when transducing HSPCs with lentiviral vectors. Efficient transduction of HSPCs requires prestimulation with c

• br Material methods br Results br Discussion

  2018-11-06

  

  Material & methods Results Discussion Several LSC culture systems have been developed to re-create the LSC niche in vitro and to avoid the cross-contamination with non-human feeder Z DEVD FMK (Sharma et al., 2012; Xie et al., 2012; Chen et al., 2013; Mei et al., 2014). It has been suggested

• It is known that radiation also

  2018-11-06

  

  It is known that radiation also alters the SVZ microenvironment. Using a computed tomography-guided localized radiation technique, a study demonstrated that the intact SVZ NSCs failed to migrate across the irradiated RMS, suggesting that the microenvironment becomes hostile for cell invasion after r

• br Materials and methods br Acknowledgments

  2018-11-06

  

  Materials and methods Acknowledgments This work was supported by grants from the National Basic Research Program of China (973 program, 2011CB964901 and 2012CB944901). We thank the genetic laboratory and IVF team of the Reproductive & Genetic Hospital of CITIC-Xiangya for their assistance.

• Let us consider in detail the main results

  2018-11-05

  

  Let us consider in detail the main results of the measurements. The laser ablation threshold density in the microsecond and nanosecond ranges depending on the sample light transmittance of nanocomposites for five samples of SiO2 coatings is shown in the graphs of Fig. 4a. These dependencies were f

• br Conclusions The results of the analysis lead us

  2018-11-05

  

  Conclusions The results of the analysis lead us to conclude that the EDD acoustic spectra in the studied frequency and temperature ranges are better described by the thermodynamic theory of acoustic relaxation rather than by the non-local diffusion theory. It has been demonstrated that within the

• As a comparison Fig d shows the

  2018-11-05

  

  As a comparison, Fig. 2d shows the shape of the curve for the probe approaching the measured sample (curve 2) for the case when the standard system for detecting the position of the probe tip is used. This system is based on the principle of registering the position of the laser beam reflected from

• Among racially ethnically diverse populations

  2018-11-05

  

  Among racially/ ethnically diverse populations, aspects of social Urea such as a sense of belonging and having a shared cultural identity have been cited as protective characteristics that promote health in these communities (Angel & Angel, 2006). There is also some evidence to suggest that residi

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