• br Acknowledgement br Introduction Murraya paniculata

  2018-11-06

  

  Acknowledgement Introduction Murraya paniculata (L.) belongs to the Rutaceae family. This plant is native to areas in Southeast Asia [1], such as Southern China, Vietnam and Malay Peninsula. In China, the ornamental plant M. paniculata is widely cultivated on the sides of the road for decorati

• br Ethical approval br Conflict of interest br

  2018-11-06

  

  Ethical approval Conflict of interest Acknowledgements We thank the Australian Government\'s Cooperative Research Centre Program and the China Scholarship Council for financial support. We would also like to acknowledge the support of staff from the Postharvest Biosecurity and Food Safety L

• br Integrin Expression in Human Stem

  2018-11-06

  

  Integrin Expression in Human Stem Cells Integrin expression in human embryonic stem spleen tyrosine kinase and selected adult stem cell types is summarised in Table 2. We define here the known expression profiles of integrins on human stem cells of four different types: embryonic, mesenchymal, h

• Previous experiments with mouse chimaeras and X

  2018-11-06

  

  Previous experiments with mouse chimaeras and X-inactivation mosaics (Collinson et al., 2002, 2004; Mort et al., 2009) suggested that the numbers of active LESC clones decline with age in wild-type mice and are reduced in Pax6+/− heterozygotes. Although this would imply that LESC function is deficie

• Ventricular cardiomyocytes VCMs are the

  2018-11-06

  

  Ventricular cardiomyocytes (VCMs) are the most extensively injured cardiac cell type in ischemic heart disease and, as a result, the leading cause of reduced cardiac function. Therefore, it is of great interest to generate a renewable source of VCMs from ESCs for cell-based therapies to treat heart

• It appears that epigenetic memory which may reflect the

  2018-11-06

  

  It appears that epigenetic memory, which may reflect the patient\'s age, is not always preserved in these iPS Zalcitabine and therefore the addition of substrates to reflect aging or long-term studies both in vitro and in vivo may be required (Lee and Studer, 2010). Imprinted genes examined in huma

• Inner pillar cells express Fgfr which

  2018-11-06

  

  Inner pillar cells express Fgfr3, which may contribute to their capacity for regeneration (Jacques et al., 2007). Supporting cells in the chicken basilar papilla express Fgfr3, which is transiently downregulated during hair cell regeneration (Bermingham-McDonogh et al., 2001). Fgfr3−/− mice lack inn

• To stage rhesus and human PGCs

  2018-11-06

  

  To stage rhesus and human PGCs, we created a heatmap of diagnostic genes that represent early PGCs (prior to DAZL and VASA expression), late PGCs (DAZL and VASA positive but prior to the emergence of major sex-specific transcriptional differences), advanced PGCs (enrichment of the male-specific gene

• Direct genetic reprogramming of postnatal

  2018-11-06

  

  Direct genetic reprogramming of postnatal primary cells by forced expression of key developmental transcription factors has emerged as an alternative to in vitro differentiation of PSCs. This strategy has been used successfully to produce functional cells, including neurons, hepatocyte-like cells an

• Compared to the adherent monolayer culture

  2018-11-06

  

  Compared to the adherent monolayer culture, an alternative method using suspension culture has been shown to be more effective in obtaining and maintaining the early neural histone demethylase inhibitor emerged during multi-staged differentiation process. Using serum-free medium supplemented with e

• With regard to the functional analysis

  2018-11-06

  

  With regard to the functional analysis of DSCs and HGF-1, several in vitro tests were performed with endothelial glucose assay (HMEC-1) to assess their influence on the different steps of the angiogenic process. Despite the expression of multiple mitogens such as VEGF, EDN1, DPPIV and ANG, DSCs were

• br Materials and methods br Results br Discussion Obesity re

  2018-11-06

  

  Materials and methods Results Discussion Obesity results when caloric intake exceeds energy expenditure, with an increase in adipocyte size or adipocyte number (Bjorntorp, 1974; Faust et al., 1978; Johnson et al., 1971, 1978; Yu et al., 1997). In the context of adipogenesis, development app

• Studies in developmental biology have identified

  2018-11-06

  

  Studies in developmental biology have identified key regulators of morphogenetic properties, and have indicated where endogenous EMF is located in the action potentials of nerves and heart tissue, and in skeletal muscle vibrations, with frequencies elicited by rhythmic activities throughout the huma

• SAMHD emerges as a ubiquitous and potent barrier to producti

  2018-11-06

  

  SAMHD1 emerges as a ubiquitous and potent barrier to productive HIV-1 infection in DCs, myeloid cells, and resting CD4+ T cells. Thus, it appeared likely that SAMHD1 might also be effective when transducing HSPCs with lentiviral vectors. Efficient transduction of HSPCs requires prestimulation with c

• br Material methods br Results br Discussion

  2018-11-06

  

  Material & methods Results Discussion Several LSC culture systems have been developed to re-create the LSC niche in vitro and to avoid the cross-contamination with non-human feeder Z DEVD FMK (Sharma et al., 2012; Xie et al., 2012; Chen et al., 2013; Mei et al., 2014). It has been suggested

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