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In an effort to determine if
2023-04-25

In an effort to determine if one 5ARI was more effective than the other, the Enlarged Prostate International Comparator Study (EPICS) [17] compared treatment with finasteride and dutasteride in 1630 men over the age of 50 and concluded that after one year of treatment, both groups had statistically
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Introduction Enzymatic browning degrades quality safety and
2023-04-21

Introduction Enzymatic browning degrades quality, safety, and nutritional values of various fruits or vegetable products. For example, the color of apple or potato is generally yellowish, representing freshness. However, they are extremely susceptible to enzymatic browning because of abundant polyp
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br Antibiotic drug discovery approaches Traditionally novel
2023-04-21

Antibiotic drug discovery approaches Traditionally, novel Garcinol were largely discovered by phenotypic screening approaches of various sources of compounds, such as natural products isolated from extracts of soil microbes and semi-synthetic or fully synthetic compound libraries derived from kn
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br Conclusions br Acknowledgments br Introduction The
2023-04-21

Conclusions Acknowledgments Introduction The surface water bodies are affected by effluents containing pollutants from wastewater treatment plants, storm water overflows and run-off from non-point sources like agricultural land and urban city surfaces. This relates to land-based sources occ
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AR is expressed in cell specific human ovarian follicles
2023-04-21

AR is expressed in cell-specific human ovarian follicles at all stages of follicular development [25]. Administration of androgens in animals demonstrated initiation of follicular recruitment, stimulation of early stages of follicular growth, and increase in the number of growing follicles [26,27].
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Fish aminopeptidases from Alaska Pollack roe and tuna
2023-04-21

Fish aminopeptidases from Alaska Pollack roe and tuna pyloric caeca have been reported on [12,13]. More recently, we described the purification of a leucine aminopeptidase from the skeletal muscle of the common carp [14], red sea bream [15] and a lysine aminopeptidases from Japanese flounder [16]. T
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AVE 0991 synthesis Ambient levels of ppm ozone were recorded
2023-04-21

Ambient levels of 0.2ppm ozone were recorded during a recent 2017 weather event in Texas, United States (EPA, 2007). This concentration or higher levels have been used in several human clinical studies during intermittent exercise (Miller et al., 2016c). Although ozone concentration of 0.8ppm used i
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Role of APPL in endosomal signaling pathways Endosomes consi
2023-04-21

Role of APPL in endosomal signaling pathways Endosomes consist of distinct membrane subdomains within individual organelles and assist in the translation of extracellular stimuli via cytoplasmic transduction cascades to the nucleus [3], [74]. Endosomal abnormalities are associated with the pathogen
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In order to investigate their effects in vitro therefore we
2023-04-20

In order to investigate their effects in vitro, therefore, we first used TE671 cells, which have provided a useful source of human AChR for in vitro and radioimmunoassay studies. We found no marked effect of either MuSK-MG or SNMG sera on AChR numbers or on AChR subunit expression. This appears to c
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As described in the introductory section the rotifer nervous
2023-04-20

As described in the introductory section, the rotifer nervous system would be capable to transmit Glycopyrrolate in throughout its neural pathways. In addition, Clément and Amsellem (1989) and Kotikova et al. (2001) suggested acetylcholine to be important for the functioning of rotifer muscles and
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VU 0364439 Matsuzaki et al attempted fertility
2023-04-20

Matsuzaki et al. attempted fertility therapy in a 26-year-old female with secondary amenorrhea and 17OHD who was a VU 0364439 heterozygote for delF53/54 and the missense mutation H373L, which has cycle supports this theory. Oocyte dysfunction with decreased granulosa cell activity might also contr
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br The complementary role of chaperone mediated autophagy Ch
2023-04-20

The complementary role of chaperone mediated autophagy Chaperone-mediated autophagy (CMA) mediates the degradation of specific cellular proteins and participates in the regulation of lipid metabolism, DNA repair, or the response to stress (Kaushik and Cuervo, 2018). CMA provides an alternative pa
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br Acknowledgments br Introduction Human innate immune syste
2023-04-20

Acknowledgments Introduction Human innate immune system provides first line of defense against multiple viral or bacterial attacks, and provides critical surveillance against oncogenic development. Evidences show that individuals with primary immunodeficiency or induced immunosuppression durin
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Inflammations lead to the perturbation of aromatase enzyme w
2023-04-20

Inflammations lead to the perturbation of aromatase enzyme [112], which normally is responsible for a broad array of critical functions. Chemotherapy targets this enzyme, so this treatment option is never side-effect-free and not fully-effective. Therefore, the mankind should be careful so as not to
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There is a delicate balance between
2023-04-20

There is a delicate balance between ROS generation and scavenging by the protective antioxidant defenses in the cell. Antioxidant systems present in the ESI-09 australia include enzymes like superoxide dismutase (SOD), catalases, glutathione peroxidases (GPxs) and peroxiredoxins (PRxs) (Fig. 3) [38
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